Core Axis
Core Axis Thyroid Support — bottle in hand against a soft chalk background

Built for
Hashimoto's.
Not for everyone else.

Ten clinical-grade compounds. Active forms only. Three capsules, once a day.

Begin protocol — $24.99 / month→
10
Active compounds
2,094.9 mg
Total actives per dose
3rd-party
Tested every lot
cGMP
Manufactured in California

A multivitamin
won't fix this.

Three things multivitamins get wrong
01

They use the wrong form of B vitamins.

Most multivitamins contain folic acid and cyanocobalamin — synthetic forms your body has to convert before it can use them. Up to 30% of people with Hashimoto’s carry a common gene variant (MTHFR) that makes that conversion slow or incomplete.

Most others
Folic acid
Cyanocobalamin
Synthetic · requires conversion
Core Axis
L-5-MTHF
Methylcobalamin
Active · ready to use
02

They under-dose what works.

In peer-reviewed trials, selenium reduces thyroid antibodies at doses around 100 µg per day. Most multivitamins contain 25 µg — a quarter of the clinical dose. You feel like you’re doing something. The biology doesn’t move.

Selenium · daily dose
Most others
25 µg
Clinical dose
100 µg
Core Axis
100 µg
Source: Toulis et al., Thyroid (2010); Gärtner et al., JCEM (2002)
03

They hide the formula behind “proprietary blends”.

Common practice: list ingredients with one combined weight, so you never know how much of each is actually in the capsule. We list every actor, every salt, every milligram on the bottle and on this page.

Most labels
Thyroid Support Blend™   450 mg †
(Ashwagandha, kelp, L-tyrosine,
schisandra, bladderwrack, …)
† PROPRIETARY · DOSES NOT DISCLOSED
Core Axis label
Selenium · L-Selenomethionine100 µg
Vitamin B12 · Methylcobalamin500 µg
Folate · L-5-MTHF400 µg
Zinc · bisglycinate15 mg
EVERY ACTOR · EVERY DOSE
§ 03 · Inside the capsule

Even the capsule is clean.

Plant-based shell. No fillers, no dyes, no shortcuts.

§ 04 · The formulation

Ten actors.
One protocol.

The complete daily panel — every active, every salt, every dose, every role. Printed here, on the bottle, and on every certificate of analysis. Hover any tile or row for context.

10 active compoundsVitaminsMineralsSynergists
#ActorFormDose%DVRole
01Myo-InositolPharmaceutical-grade600mg—Synergist with selenium; supports TSH normalization in autoimmune thyroiditis.
02SeleniumL-Selenomethionine100µg182%Reduces TPO antibody titers; cofactor for T4→T3 deiodinase enzymes.
03ZincZinc bisglycinate15mg136%Cofactor for thyroid hormone synthesis and TSH receptor function.
04Vitamin D3Cholecalciferol (2,000 IU)50µg250%Modulates immune response in autoimmune thyroiditis.
05Vitamin B6Pyridoxal 5'-phosphate (P-5-P)3mg176%Active form; supports methylation pathways.
06FolateL-5-MTHF Calcium400µg100%Bioavailable folate for MTHFR variants.
07Vitamin B12Methylcobalamin500µg20833%Active form; corrects common Hashimoto deficiency.
08Vitamin CCalcium ascorbate100mg111%Antioxidant; supports adrenal & immune function.
09MagnesiumMagnesium bisglycinate150mg36%Reduces TSH variability; supports sleep architecture.
10S-acetyl-glutathioneAcetylated tripeptide100mg—Stable, oral-bioavailable master antioxidant.
ΣTotal active mass2,094.9mgVegetal capsule. No magnesium stearate, no titanium dioxide, no synthetic colorants.
Download specifications (PDF)Certificate of analysis

Four failures.
Four answers.

Hashimoto's isn't one failure — it's a cascade. Immune dysregulation triggers oxidative stress, which blunts hormone conversion, which collapses methylation. CoreAxis intervenes at every link.

The problemThe intervention
L01

Immune dysregulation

Vit D₃ · Selenium · GSH

Immune modulation

TPO antibodies fall. Th1/Th17 polarization dampens. The autoimmune driver is reined in.

L02

Oxidative stress

GSH · Vit C · Zinc

Antioxidant defense

Reactive oxygen species generated by chronic thyroid inflammation are neutralized at the source.

L03

Blunted T4 → T3

Selenium · Zinc · Mg

Hormone conversion

Type-1 and type-2 deiodinases come back online. Active T3 — the form your cells actually use — gets produced.

L04

Methylation breakdown

B₆ · B₉ · B₁₂ · Mg

Energy & cognition

Methylation cycle restored. The persistent fatigue and brain fog that lab numbers miss begin to lift.

Clément, founder of Core Axis, in Hakone
Hakone · 2026
F · A note from the founder

I built this because nothing on the shelf worked for me.

I was diagnosed with Hashimoto's at 28. Levothyroxine brought my TSH back into range and most of my symptoms stayed. The fatigue, the brain fog, the cold — none of the twelve multivitamins I tried moved the needle.

So I spent two years reading the trials, working with an endocrinologist and a clinical nutritionist, and rebuilding what a thyroid protocol should actually look like. Core Axis is what I now take every morning.

ClémentFounder · Core Axis

Start your
first thirty days.

Most members feel a measurable shift in energy and mental clarity within three to six weeks. The protocol is designed for continuous use; subscription is the default and is recommended.

60-day clinical refundFree US shippingPause anytime
10 ACTIVES2094.9 MG90 V-CAP
§ E
Voices

What practitioners and members have observed.

N
Note 01
“The transparency is what convinced me. Every dose stated, every salt named. As a clinician, I want to know exactly what I am recommending.”
Dr. Naomi Reyes
Functional Endocrinology, Boston
M
Note 02
“I had been on three separate supplements to cover the same actives. CoreAxis consolidates them at clinical doses. My TPO antibodies dropped meaningfully over six months.”
Member · age 41
Diagnosed 2019
TPO ↓ 47% · 6 mo
A
Note 03
“A formulation I can read in thirty seconds and defend in front of a peer-review committee. That is rare in this category.”
Dr. Aaron Vogel
Internal Medicine, Chicago
§ G
Inquiries

Direct answers, in plain language.

A multivitamin is built for population-level deficiency prevention at minimum effective doses. CoreAxis is built for one autoimmune condition at therapeutic doses, using only forms with established bioavailability. The two products solve different problems.