Core Axis
core axis

Core Axis Thyroid Support

4.8 · 47 reviews
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$74.95
Formulated with Elena Vayndorf, Ph.D. · NIH

Ten clinical actives in a single vegetal capsule. Formulated specifically for Hashimoto's thyroiditis.

Methylated B vitamins, therapeutic-dose selenium, and zinc to interrupt the autoimmune cascade at its source.

60-day money-back guarantee
Free US shipping
Made in USA with imported ingredients
Third-party batch tested
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§ · The comparison

Most multivitamins, and Core Axis.

Most multivitaminsCore Axis
B-vitamin forms×Folic acid, cyanocobalaminL-5-MTHF, methylcobalamin
Selenium dose×25 µg100 µg (clinical)
Label transparency×Proprietary blendsEvery salt, every dose
Targeted condition×Population averagesHashimoto's specifically
Daily protocol×5–10 pills from 3–5 bottles3 capsules, once a day
§ · Member outcomes
72%

of members report improved energy by week 4

68%

report reduced brain fog within 30 days

31%

average TPO antibody reduction over 90 days

Based on a 90-day member outcomes survey · N=94 · Self-reported
§ · The ritual

How to take it, once a day.

01

Morning, with food

Take with breakfast or a midday meal. Food improves absorption of fat-soluble vitamins (D3).

02

Three capsules together

Swallow with water. No need to space them across the day. The full dose is designed for one moment.

03

4 hours from levothyroxine

Mineral content (zinc, selenium) requires separation from thyroid medication. Take Core Axis later in the day.

§ 04 · The formulation

Ten actors.
One protocol.

The complete daily panel: every active, every salt, every dose, every role. Printed here, on the bottle, and on every certificate of analysis. Hover any tile or row for context.

10 active compoundsVitaminsMineralsSynergists
Myo-Inositol
600mg
Pharmaceutical-grade

Supports healthy TSH signaling*; studied in combination with selenium for thyroid support.

Selenium
100µg
L-Selenomethionine · 182% DV

May support healthy thyroid antibody balance*; supports T4→T3 thyroid hormone conversion*

Zinc
15mg
Zinc bisglycinate · 136% DV

Supports thyroid hormone metabolism and T4→T3 conversion*

Vitamin D3
50µg
Cholecalciferol (2,000 IU) · 250% DV

Supports healthy immune function*; extensively researched in thyroid health contexts

Vitamin B6
3mg
Pyridoxal 5'-phosphate (P-5-P) · 176% DV

Active form; supports methylation pathways.

Folate
400µg
L-5-MTHF Calcium · 100% DV

Bioavailable folate for MTHFR variants.

Vitamin B12
500µg
Methylcobalamin · 20833% DV

Active form; supports healthy B12 status*.

Vitamin C
100mg
Calcium ascorbate · 111% DV

Antioxidant; supports normal immune function*

Magnesium
150mg
Magnesium bisglycinate · 36% DV

Supports healthy thyroid function*; supports restful sleep*

S-acetyl-glutathione
100mg
Acetylated tripeptide

Stable, cell-ready glutathione*; supports cellular antioxidant defense*

Total active mass2,094.9mg
#ActorFormDose%DVRole
01Myo-InositolPharmaceutical-grade600mgSupports healthy TSH signaling*; studied in combination with selenium for thyroid support.
02SeleniumL-Selenomethionine100µg182%May support healthy thyroid antibody balance*; supports T4→T3 thyroid hormone conversion*
03ZincZinc bisglycinate15mg136%Supports thyroid hormone metabolism and T4→T3 conversion*
04Vitamin D3Cholecalciferol (2,000 IU)50µg250%Supports healthy immune function*; extensively researched in thyroid health contexts
05Vitamin B6Pyridoxal 5'-phosphate (P-5-P)3mg176%Active form; supports methylation pathways.
06FolateL-5-MTHF Calcium400µg100%Bioavailable folate for MTHFR variants.
07Vitamin B12Methylcobalamin500µg20833%Active form; supports healthy B12 status*.
08Vitamin CCalcium ascorbate100mg111%Antioxidant; supports normal immune function*
09MagnesiumMagnesium bisglycinate150mg36%Supports healthy thyroid function*; supports restful sleep*
10S-acetyl-glutathioneAcetylated tripeptide100mgStable, cell-ready glutathione*; supports cellular antioxidant defense*
ΣTotal active mass2,094.9mgVegetal capsule. No titanium dioxide, no synthetic colorants.
§ 06 · Members

In their own words.

Sofia R.
Member · Hashimoto since 2020

"Finally something that works at the right dose."

Sarah M.
Member · Hashimoto since 2019

"My energy came back. Six weeks in."

Laura L.
Member · Hashimoto since 2022

"The formula is fully transparent. That is rare."

Customer Reviews
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4.8
across 47 reviews
4.8 out of 5
5
73%
4
18%
3
6%
2
2%
1
1%
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Customers say · AI Summary

Customers consistently report improved energy and mental clarity within the first three to four weeks. Many specifically mention the methylated vitamin forms as the reason it works when other supplements did not, particularly those with the MTHFR mutation. Formula transparency and lab-verified dosing come up repeatedly as the deciding factor before buying. A minority note mild digestive adjustment in the first few days if taken without food.

energybrain fogMTHFRantibodiesabsorptionlevothyroxine
Synthesized from 47 verified reviews
SM
Sarah M.
Finally something that works
Reviewed on Feb 14, 2026

Three months in and my brain fog has lifted a lot. My endocrinologist actually noticed it too. My TPO antibodies went from 340 to 210 on my last panel. I was skeptical at first but the fact that every ingredient is listed with the exact dose is what convinced me to try it.

CD
Claire D.
The methylated forms make a real difference
Reviewed on Jan 9, 2026

Tried a lot of thyroid supplements before this one. The methylcobalamin and L-5-MTHF stood out to me right away since I have the MTHFR mutation. Those forms actually get absorbed. First time in about two years I have woken up without feeling completely wiped out.

ML
Marie L.
Noticeable shift by week 4
Reviewed on Mar 3, 2026

Energy is better, no question. Lab work is next month so I cannot say anything about antibodies yet. Small thing: take it with food and really mean it. Skipped the meal once and felt off for the rest of the day. Other than that, really happy with it.

IR
Isabelle R.
My rheumatologist approved the formula
Reviewed on Nov 22, 2025

Showed the formula to my rheumatologist before starting. She said the selenium dosage is appropriate and the vitamin forms are what she would have chosen herself. Having a doctor sign off on it before buying made a big difference for me.

60-day money-back guarantee

If you're not fully satisfied within sixty days, we refund you fully.

Keep the bottles. No labs required, no return shipping, no questions beyond the one we ask ourselves: did it work for you? Apply via your account or email hello@coreaxis.us.

§ · Before you buy

The four questions you'll want answered.

Yes, with a four-hour separation. Standard for any mineral-containing supplement. Take levothyroxine on waking, Core Axis with a midday meal.

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