Ten clinical actives in a single vegetal capsule. Formulated specifically for Hashimoto's thyroiditis.
Methylated B vitamins, therapeutic-dose selenium, and zinc to interrupt the autoimmune cascade at its source.

of members report improved energy by week 4
report reduced brain fog within 30 days
average TPO antibody reduction over 90 days
Take with breakfast or a midday meal. Food improves absorption of fat-soluble vitamins (D3).
Swallow with water. No need to space them across the day. The full dose is designed for one moment.
Mineral content (zinc, selenium) requires separation from thyroid medication. Take Core Axis later in the day.
The complete daily panel: every active, every salt, every dose, every role. Printed here, on the bottle, and on every certificate of analysis. Hover any tile or row for context.
Supports healthy TSH signaling*; studied in combination with selenium for thyroid support.
May support healthy thyroid antibody balance*; supports T4→T3 thyroid hormone conversion*
Supports thyroid hormone metabolism and T4→T3 conversion*
Supports healthy immune function*; extensively researched in thyroid health contexts
Active form; supports methylation pathways.
Bioavailable folate for MTHFR variants.
Active form; supports healthy B12 status*.
Antioxidant; supports normal immune function*
Supports healthy thyroid function*; supports restful sleep*
Stable, cell-ready glutathione*; supports cellular antioxidant defense*
"Finally something that works at the right dose."
"My energy came back. Six weeks in."
"The formula is fully transparent. That is rare."
Customers consistently report improved energy and mental clarity within the first three to four weeks. Many specifically mention the methylated vitamin forms as the reason it works when other supplements did not, particularly those with the MTHFR mutation. Formula transparency and lab-verified dosing come up repeatedly as the deciding factor before buying. A minority note mild digestive adjustment in the first few days if taken without food.
Three months in and my brain fog has lifted a lot. My endocrinologist actually noticed it too. My TPO antibodies went from 340 to 210 on my last panel. I was skeptical at first but the fact that every ingredient is listed with the exact dose is what convinced me to try it.
Tried a lot of thyroid supplements before this one. The methylcobalamin and L-5-MTHF stood out to me right away since I have the MTHFR mutation. Those forms actually get absorbed. First time in about two years I have woken up without feeling completely wiped out.
Energy is better, no question. Lab work is next month so I cannot say anything about antibodies yet. Small thing: take it with food and really mean it. Skipped the meal once and felt off for the rest of the day. Other than that, really happy with it.
Showed the formula to my rheumatologist before starting. She said the selenium dosage is appropriate and the vitamin forms are what she would have chosen herself. Having a doctor sign off on it before buying made a big difference for me.
Keep the bottles. No labs required, no return shipping, no questions beyond the one we ask ourselves: did it work for you? Apply via your account or email hello@coreaxis.us.
Yes, with a four-hour separation. Standard for any mineral-containing supplement. Take levothyroxine on waking, Core Axis with a midday meal.